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Molecular Pathways: Activating T Cells After Cancer Cell Phagocytosis from Blockade of CD47 “Don’t Eat Me” Signals

Recent advances with immunotherapy agents for the treatment of cancer has provided remarkable, and in some cases, curative results. Our laboratory has identified CD47 as an important “don’t eat me” signal expressed on malignant cells. Blockade of the CD47:SIRP-α axis between tumor cells and innate i...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: McCracken, Melissa N., Cha, Adriel C., Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621226/
https://ncbi.nlm.nih.gov/pubmed/26116271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2520
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