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Molecular Pathways: Activating T Cells After Cancer Cell Phagocytosis from Blockade of CD47 “Don’t Eat Me” Signals

Recent advances with immunotherapy agents for the treatment of cancer has provided remarkable, and in some cases, curative results. Our laboratory has identified CD47 as an important “don’t eat me” signal expressed on malignant cells. Blockade of the CD47:SIRP-α axis between tumor cells and innate i...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: McCracken, Melissa N., Cha, Adriel C., Weissman, Irving L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621226/
https://ncbi.nlm.nih.gov/pubmed/26116271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2520
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