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Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase

Toxin–antitoxin (TA) systems are implicated in the downregulation of bacterial cell growth associated with stress survival and latent tuberculosis infection, yet the activities and intracellular targets of these TA toxins are largely uncharacterized. Here, we use a specialized RNA-seq approach to id...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cruz, Jonathan W., Sharp, Jared D., Hoffer, Eric D., Maehigashi, Tatsuya, Vvedenskaya, Irina O., Konkimalla, Arvind, Husson, Robert N., Nickels, Bryce E., Dunham, Christine M., Woychik, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620994/
https://ncbi.nlm.nih.gov/pubmed/26158745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8480
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