Genome-wide modeling of transcription kinetics reveals patterns of RNA production delays

Genes with similar transcriptional activation kinetics can display very different temporal mRNA profiles because of differences in transcription time, degradation rate, and RNA-processing kinetics. Recent studies have shown that a splicing-associated RNA production delay can be significant. To inves...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Honkela, Antti, Peltonen, Jaakko, Topa, Hande, Charapitsa, Iryna, Matarese, Filomena, Grote, Korbinian, Stunnenberg, Hendrik G., Reid, George, Lawrence, Neil D., Rattray, Magnus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620908/
https://ncbi.nlm.nih.gov/pubmed/26438844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420404112
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