Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data

Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influence the rate and timing of gene expression. In this work, we present a probabilistic model of transcription dynamics which is fitted to pol-II...

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Detalhes bibliográficos
Main Authors: wa Maina, Ciira, Honkela, Antti, Matarese, Filomena, Grote, Korbinian, Stunnenberg, Hendrik G., Reid, George, Lawrence, Neil D., Rattray, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022483/
https://ncbi.nlm.nih.gov/pubmed/24830797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003598
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