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Exceptionally large entropy contributions enable the high rates of GTP hydrolysis on the ribosome
Protein synthesis on the ribosome involves hydrolysis of GTP in several key steps of the mRNA translation cycle. These steps are catalyzed by the translational GTPases of which elongation factor Tu (EF-Tu) is the fastest GTPase known. Here, we use extensive computer simulations to explore the origin...
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| 出版年: | Sci Rep |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4620562/ https://ncbi.nlm.nih.gov/pubmed/26497916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15817 |
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