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The mechanism for activation of GTP hydrolysis on the ribosome

Protein synthesis requires several GTPase factors, including Elongation Factor Tu (EF-Tu), which delivers aminoacyl-tRNAs to the ribosome. In order to understand how the ribosome triggers GTP hydrolysis in translational GTPases, we have determined the crystal structure of EF-Tu and aminoacyl-tRNA bo...

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Detalhes bibliográficos
Main Authors: Voorhees, Rebecca M., Schmeing, T. Martin, Kelley, Ann C., Ramakrishnan, V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763471/
https://ncbi.nlm.nih.gov/pubmed/21051640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1194460
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