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How mutations in tRNA distant from the anticodon affect the fidelity of decoding
The ribosome converts genetic information into protein by selecting aminoacyl-tRNAs whose anticodons base pair to an mRNA codon. Mutations in the tRNA body can perturb this process and affect fidelity. The Hirsh suppressor is a well-studied tRNA(Trp) harboring a G24A mutation that allows readthrough...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072312/ https://ncbi.nlm.nih.gov/pubmed/21378964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2003 |
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