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Trans-presentation of IL-15 modulates STAT5 activation and Bcl-6 expression in T(H)1 cells

During infection, naïve CD4(+) T helper cells differentiate into specialized effector subsets based upon environmental signals propagated by the cytokine milieu. Recently, this paradigm has been complicated by the demonstration that alterations in the cytokine environment can result in varying degre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cooley, Ian D., Read, Kaitlin A., Oestreich, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620557/
https://ncbi.nlm.nih.gov/pubmed/26500048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15722
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