Caricamento...
IL-7 signalling represses Bcl-6 and the T(FH) gene program
The transcriptional repressor Bcl-6 is linked to the development of both CD4(+) T follicular helper (T(FH)) and central memory T (T(CM)) cells. Here, we demonstrate that in response to decreased IL-2 signalling, T helper 1 (T(H)1) cells upregulate Bcl-6 and co-initiate T(FH)- and T(CM)-like gene pro...
Salvato in:
| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729877/ https://ncbi.nlm.nih.gov/pubmed/26743592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10285 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|