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Thermodynamics of protein denaturation at temperatures over 100 °C: CutA1 mutant proteins substituted with hydrophobic and charged residues

Although the thermodynamics of protein denaturation at temperatures over 100 °C is essential for the rational design of highly stable proteins, it is not understood well because of the associated technical difficulties. We designed certain hydrophobic mutant proteins of CutA1 from Escherichia coli,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsuura, Yoshinori, Takehira, Michiyo, Joti, Yasumasa, Ogasahara, Kyoko, Tanaka, Tomoyuki, Ono, Naoko, Kunishima, Naoki, Yutani, Katsuhide
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620440/
https://ncbi.nlm.nih.gov/pubmed/26497062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15545
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