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Ion–ion interactions in the denatured state contribute to the stabilization of CutA1 proteins

In order to elucidate features of the denatured state ensembles that exist in equilibrium with the native state under physiological conditions, we performed 1.4-μs molecular dynamics (MD) simulations at 400 K and 450 K using the monomer subunits of three CutA1 mutants from Escherichia coli: an SH-fr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yutani, Katsuhide, Matsuura, Yoshinori, Naitow, Hisashi, Joti, Yasumasa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955972/
https://ncbi.nlm.nih.gov/pubmed/29769700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25825-7
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