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Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE(2) Synthesis of HBx(+) Hepatocytes
We investigated the mechanism of caffeine in influencing HBx(+) hepatocytes to synthesize PGE(2). The inhibitory effect of caffeine on hepatocyte proliferation increased with increasing caffeine concentrations (200–800 μM) and treatment times (1–7 days), which was first observed at the second test t...
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| Publicado no: | Mediators Inflamm |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619973/ https://ncbi.nlm.nih.gov/pubmed/26538827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/372750 |
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