Membrane Cholesterol Modulates LOX-1 Shedding in Endothelial Cells

The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a scavenger receptor responsible for ox-LDL recognition, binding and internalization, which is up-regulated during atherogenesis. Its activation triggers endothelium dysfunction and induces inflammation. A soluble form of LOX-1 h...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Gioia, Magda, Vindigni, Giulia, Testa, Barbara, Raniolo, Sofia, Fasciglione, Giovanni Francesco, Coletta, Massimiliano, Biocca, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619672/
https://ncbi.nlm.nih.gov/pubmed/26495844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141270
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