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Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen

The proteolytic processing of bovine fibrinogen by MMP-2 (gelatinase A), which brings about the formation of a product unable to form fibrin clots, has been studied at 37 °C. Catalytic parameters, although showing a somewhat lower catalytic efficiency with respect to thrombin and plasmin, indeed dis...

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Detalhes bibliográficos
Main Authors: Monaco, Susanna, Gioia, Magda, Rodriguez, Janet, Fasciglione, Giovanni Francesco, Di Pierro, Donato, Lupidi, Giulio, Krippahl, Ludwig, Marini, Stefano, Coletta, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863560/
https://ncbi.nlm.nih.gov/pubmed/17087661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061064
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