Molecular mechanism of statin-mediated LOX-1 inhibition

Statins are largely used in clinics in the treatment of patients with cardiovascular diseases for their effect on lowering circulating cholesterol. Lectin-like oxidized low-density lipoprotein (LOX-1), the primary receptor for ox-LDL, plays a central role in the pathogenesis of atherosclerosis and c...

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Vydáno v:Cell Cycle
Hlavní autoři: Biocca, Silvia, Iacovelli, Federico, Matarazzo, Sara, Vindigni, Giulia, Oteri, Francesco, Desideri, Alessandro, Falconi, Mattia
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614984/
https://ncbi.nlm.nih.gov/pubmed/25950192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026486
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