Histone acetylation regulates prostate ductal morphogenesis through a BMP dependent mechanism

BACKGROUND: Epigenetic factors influence stem cell function and other developmental events but their role in prostate morphogenesis is not completely known. We tested the hypothesis that histone deacetylase (HDAC) activity is required for prostate morphogenesis. RESULTS: We identified the presence o...

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Veröffentlicht in:Dev Dyn
Hauptverfasser: Keil, Kimberly P., Altmann, Helene M., Abler, Lisa L., Hernandez, Laura L., Vezina, Chad M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619142/
https://ncbi.nlm.nih.gov/pubmed/26283270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24321
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