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DNA methylation of E-cadherin is a priming mechanism for prostate development
In prostate and other epithelial cancers, E-cadherin (CDH1) is downregulated inappropriately by DNA methylation to promote an invasive phenotype. Though cancer frequently involves a reawakening of developmental signaling pathways, whether DNA methylation of Cdh1 occurs during organogenesis has not b...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976955/ https://ncbi.nlm.nih.gov/pubmed/24503032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.01.020 |
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