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Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development

Androgen receptor (AR) signaling initiates mouse prostate development by stimulating prostate ductal bud formation and specifying bud patterns. Curiously, however, prostatic bud initiation lags behind the onset of gonadal testosterone synthesis by about three days. This study’s objective was to test...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Keil, Kimberly P., Abler, Lisa L., Laporta, Jimena, Altmann, Helene M., Yang, Bing, Jarrard, David F., Hernandez, Laura L., Vezina, Chad M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261055/
https://ncbi.nlm.nih.gov/pubmed/25446526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.10.006
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