Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development

Androgen receptor (AR) signaling initiates mouse prostate development by stimulating prostate ductal bud formation and specifying bud patterns. Curiously, however, prostatic bud initiation lags behind the onset of gonadal testosterone synthesis by about three days. This study’s objective was to test...

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Veröffentlicht in:Dev Biol
Hauptverfasser: Keil, Kimberly P., Abler, Lisa L., Laporta, Jimena, Altmann, Helene M., Yang, Bing, Jarrard, David F., Hernandez, Laura L., Vezina, Chad M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261055/
https://ncbi.nlm.nih.gov/pubmed/25446526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.10.006
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