Characterization of Frog Virus 3 Knockout Mutants Lacking Putative Virulence Genes

To identify ranavirus virulence genes, we engineered Frog Virus 3 (FV3) knockout (KO) mutants defective for a putative viral caspase activation and recruitment domain-containing (CARD) protein (Δ64R-FV3) and a β-hydroxysteroid dehydrogenase homolog (Δ52L-FV3). Compared to wild type (WT) FV3, infecti...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: De Jesús Andino, Francisco, Grayfer, Leon, Chen, Guangchun, Chinchar, V. Gregory, Edholm, Eva-Stina, Robert, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619136/
https://ncbi.nlm.nih.gov/pubmed/26264970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.07.011
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