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Susceptibility of Xenopus laevis tadpoles to infection by the ranavirus Frog-Virus 3 correlates with a reduced and delayed innate immune response in comparison with adult frogs

Xenopus laevis adults mount effective immune responses to ranavirus Frog Virus 3 (FV3) infections and clear the pathogen within 2–3 weeks. In contrast, most tadpoles cannot clear FV3 and succumb to infections within a month. While larval susceptibility has been attributed to ineffective adaptive imm...

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Detalhes bibliográficos
Main Authors: De Jesús Andino, Francisco, Chen, Guangchun, Li, Zhenghui, Grayfer, Leon, Robert, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574294/
https://ncbi.nlm.nih.gov/pubmed/22819836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.07.001
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