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Phylogenomics and sequence-structure-function relationships in the GmrSD family of Type IV restriction enzymes

BACKGROUND: GmrSD is a modification-dependent restriction endonuclease that specifically targets and cleaves glucosylated hydroxymethylcytosine (glc-HMC) modified DNA. It is encoded either as two separate single-domain GmrS and GmrD proteins or as a single protein carrying both domains. Previous stu...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Machnicka, Magdalena A., Kaminska, Katarzyna H., Dunin-Horkawicz, Stanislaw, Bujnicki, Janusz M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619093/
https://ncbi.nlm.nih.gov/pubmed/26493560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0773-z
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