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DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs
BACKGROUND: CRISPR genome-editing technology makes it possible to quickly and cheaply delete non-protein-coding regulatory elements. We present a vector system adapted for this purpose called DECKO (Double Excision CRISPR Knockout), which applies a simple two-step cloning to generate lentiviral vect...
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| Udgivet i: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619085/ https://ncbi.nlm.nih.gov/pubmed/26493208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2086-z |
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