TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma

Viral infections are a common cause of asthma exacerbation. These maladies are sometimes complicated by bacterial infections. Toll-like receptors (TLRs) are in the forefront of our microbial defence, with TLR3 responding to viral and TLR4 to bacterial stimulation. The present study was designed to e...

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Vydáno v:Respir Res
Hlavní autoři: Starkhammar, Magnus, Kumlien Georén, Susanna, Dahlén, Sven-Erik, Cardell, Lars-Olaf, Adner, Mikael
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618779/
https://ncbi.nlm.nih.gov/pubmed/26494305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0292-5
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