Toll-Like Receptor Ligands LPS and Poly (I:C) Exacerbate Airway Hyperresponsiveness in a Model of Airway Allergy in Mice, Independently of Inflammation

It is well-established that bacterial and viral infections have an exacerbating effect on allergic asthma, particularly aggravating respiratory symptoms, such as airway hyperresponsiveness (AHR). The mechanism by which these infections alter AHR is unclear, but some studies suggest that Toll-like re...

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Opis bibliograficzny
Główni autorzy: Starkhammar, Magnus, Larsson, Olivia, Kumlien Georén, Susanna, Leino, Marina, Dahlén, Sven-Erik, Adner, Mikael, Cardell, Lars-Olaf
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121312/
https://ncbi.nlm.nih.gov/pubmed/25089623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104114
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