Manganese Potentiates Nuclear Factor-κB-Dependent Expression of Nitric Oxide Synthase 2 in Astrocytes by Activating Soluble Guanylate Cyclase and Extracellular Responsive Kinase Signaling Pathways

Inflammatory activation of glial cells is associated with neuronal injury in several degenerative movement disorders of the basal ganglia, including manganese neurotoxicity. Manganese (Mn) potentiates the effects of inflammatory cytokines on nuclear factor-κB (NF-κB)-dependent expression of nitric o...

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Vydáno v:J Neurosci Res
Hlavní autoři: Moreno, Julie A., Sullivan, Kelly A., Carbone, David L., Hanneman, William H., Tjalkens, Ronald B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618683/
https://ncbi.nlm.nih.gov/pubmed/18335517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21640
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