Resistance detected by pyrosequencing following zidovudine-monotherapy for prevention of HIV-1 mother-to-child-transmission

To prevent mother-to-child-transmission-of-HIV-1, the 2010 WHO guidelines recommended prenatal zidovudine monotherapy (Option A). To determine if ZDV-monotherapy selects for HIV-resistance in antiretroviral-naïve women during pregnancy, specimens from 50 were examined using pyrosequencing. ZDV-resis...

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Bibliografske podrobnosti
izdano v:AIDS
Main Authors: Olson, Scott C., Ngo-Giang-Huong, Nicole, Beck, Ingrid, Deng, Wenjie, Britto, Paula, Shapiro, David E., Bumgarner, Roger E., Mullins, James I., Van Dyke, Russell B., Jourdain, Gonzague, Frenkel, Lisa M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618483/
https://ncbi.nlm.nih.gov/pubmed/26244386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000737
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