Suppressors of superoxide production from mitochondrial complex III

Mitochondrial electron transport drives ATP synthesis but also generates reactive oxygen species (ROS), which are both cellular signals and damaging oxidants. Superoxide production by respiratory complex III is implicated in diverse signaling events and pathologies but its role remains controversial...

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Publicado en:Nat Chem Biol
Main Authors: Orr, Adam L., Vargas, Leonardo, Turk, Carolina N., Baaten, Janine E., Matzen, Jason T., Dardov, Victoria J., Attle, Stephen J., Li, Jing, Quackenbush, Douglas C., Goncalves, Renata L. S., Perevoshchikova, Irina V., Petrassi, H. Michael, Meeusen, Shelly L., Ainscow, Edward K., Brand, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618194/
https://ncbi.nlm.nih.gov/pubmed/26368590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1910
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