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Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress

DNA damage and DNA damage response (DDR) in neurulation stage embryos under maternal diabetes conditions are not well understood. The purpose of this study was to investigate whether maternal diabetes and high glucose in vitro induce DNA damage and DDR in the developing embryo through oxidative stre...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Dong, Daoyin, Yu, Jingwen, Wu, Yanqing, Fu, Noah, Villela, Natalia Arias, Yang, Peixin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618162/
https://ncbi.nlm.nih.gov/pubmed/26427872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.09.137
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