Wordt geladen...
Leukotriene C(4) is the major trigger of stress-induced oxidative DNA damage
Endoplasmic reticulum (ER) stress and major chemotherapeutic agents damage DNA by generating reactive oxygen species (ROS). Here we show that ER stress and chemotherapy induce leukotriene C(4) (LTC(4)) biosynthesis by transcriptionally upregulating and activating the enzyme microsomal glutathione-S-...
Bewaard in:
| Gepubliceerd in: | Nat Commun |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2015
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682057/ https://ncbi.nlm.nih.gov/pubmed/26656251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10112 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|