Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined ‘narrow’ repertoire

T cell receptor (TCR) usage plays an important role in determining the outcome of CD8+ cytotoxic T lymphocyte (CTL) responses to viruses and other pathogens. However, the characterization of TCR usage from which such conclusions are drawn, is based on exclusive analysis of either the TCRα or, more c...

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Publicat a:Immunol Cell Biol
Autors principals: Cukalac, Tania, Kan, Wan-Ting, Dash, Pradyot, Guan, Jing, Quinn, Kylie M., Gras, Stephanie, Thomas, Paul G., La Gruta, Nicole L.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618100/
https://ncbi.nlm.nih.gov/pubmed/25804828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.44
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