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Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells?

Cellular drug resistance, which involves several mechanisms such as P‐glycoprotein (P‐gp) overexpression, kinetic and metabolic quiescence, or the increase in the intracellular levels of glutathione, limits the effectiveness of cancer treatment. It has been reported that functional assessment of the...

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Publicat a:Anal Cell Pathol
Autors principals: Pétriz, Jordi, O’Connor, José Enrique, Carmona, Mercè, García‐López, Joan
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617575/
https://ncbi.nlm.nih.gov/pubmed/9354229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1997/645731
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