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Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair

Transcription factor IIH (TFIIH) is essential for both transcription and nucleotide excision repair (NER). DNA lesions are initially detected by NER factors XPC and XPE or stalled RNA polymerases, but only bulky lesions are preferentially repaired by NER. To elucidate substrate specificity in NER, w...

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Vydáno v:Mol Cell
Hlavní autoři: Li, Chia-Lung, Golebiowski, Filip M., Onishi, Yuki, Samara, Nadine L., Sugasawa, Kaoru, Yang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617536/
https://ncbi.nlm.nih.gov/pubmed/26384665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.012
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