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Tripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair

Transcription factor IIH (TFIIH) is essential for both transcription and nucleotide excision repair (NER). DNA lesions are initially detected by NER factors XPC and XPE or stalled RNA polymerases, but only bulky lesions are preferentially repaired by NER. To elucidate substrate specificity in NER, w...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Li, Chia-Lung, Golebiowski, Filip M., Onishi, Yuki, Samara, Nadine L., Sugasawa, Kaoru, Yang, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617536/
https://ncbi.nlm.nih.gov/pubmed/26384665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.012
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