Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss

The phosphodiesterase inhibitor (PDEI)/eNOS enhancer KMUP-1, targeting G-protein coupled receptors (GPCRs), improves dyslipidemia. We compared its lipid-lowering effects with simvastatin and explored hormone-sensitive lipase (HSL) translocation in hepatic fat loss. KMUP-1 HCl (1, 2.5, and 5 mg/kg/da...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Kuo, Kung-Kai, Wu, Bin-Nan, Liu, Chung-Pin, Yang, Tzu-Yang, Kao, Li-Pin, Wu, Jiunn-Ren, Lai, Wen-Ter, Chen, Ing-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617394/
https://ncbi.nlm.nih.gov/pubmed/26351364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M057547
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados