Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia

Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role. Zebrafish are a useful model for studying the genetic susceptibility to hyper...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: O’Hare, Elizabeth A., Wang, Xiaochun, Montasser, May E., Chang, Yen-Pei C., Mitchell, Braxton D., Zaghloul, Norann A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617127/
https://ncbi.nlm.nih.gov/pubmed/25201834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M046540
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