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Synthetic self-adjuvanting glycopeptide cancer vaccines

Due to changes in glycosyltransferase expression during oncogenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells. These glycans are known as tumor-associated carbohydrate antigens (TACAs), and are prime targets for use in vacc...

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Bibliografiske detaljer
Udgivet i:Front Chem
Main Authors: McDonald, David M., Byrne, Scott N., Payne, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615963/
https://ncbi.nlm.nih.gov/pubmed/26557640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00060
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