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Synthetic self-adjuvanting glycopeptide cancer vaccines

Due to changes in glycosyltransferase expression during oncogenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells. These glycans are known as tumor-associated carbohydrate antigens (TACAs), and are prime targets for use in vacc...

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Podrobná bibliografie
Vydáno v:Front Chem
Hlavní autoři: McDonald, David M., Byrne, Scott N., Payne, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615963/
https://ncbi.nlm.nih.gov/pubmed/26557640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00060
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