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Nuclear mechanotransduction: Forcing the nucleus to respond

Cell phenotype and fate are driven by the mechanical properties of their surrounding environment. Changes in matrix rigidity or application of force have been shown to impact profoundly cell behavior and phenotype, demonstrating that the molecular mechanisms which “sense” and transduce these signals...

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Bibliografiske detaljer
Udgivet i:Nucleus
Main Authors: Guilluy, Christophe, Burridge, Keith
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615784/
https://ncbi.nlm.nih.gov/pubmed/25738642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2014.1001705
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