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Characterization of binding of LARP6 to the 5’ stem-loop of collagen mRNAs: Implications for synthesis of type I collagen

Type I collagen is composed of 2 polypeptides, α1(I) and α2(I), which fold into triple helix. Collagen α1(I) and α2(I) mRNAs have a conserved stem-loop structure in their 5’ UTRs, the 5’SL. LARP6 binds the 5’SL to regulate type I collagen expression. We show that 5 nucleotides within the single stra...

詳細記述

保存先:
書誌詳細
出版年:RNA Biol
主要な著者: Stefanovic, Lela, Longo, Liam, Zhang, Yujie, Stefanovic, Branko
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615758/
https://ncbi.nlm.nih.gov/pubmed/25692237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2014.996467
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