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A Novel Role of Vimentin Filaments: Binding and Stabilization of Collagen mRNAs
The stem-loop in the 5′ untranslated region (UTR) of collagen α1(I) and α2(I) mRNAs (5′SL) is the key element regulating their stability and translation. Stabilization of collagen mRNAs is the predominant mechanism for high collagen expression in fibrosis. LARP6 binds the 5′SL of α1(I) and α2(I) mRN...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165730/ https://ncbi.nlm.nih.gov/pubmed/21746880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05263-11 |
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