β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation

BACKGROUND: Invariant Natural Killer T (iNKT) cells have been implicated in lung inflammation in humans and also shown to be a key cell type in inducing allergic lung inflammation in mouse models. iNKT cells differentiate and acquire functional characteristics during development in the thymus. Howev...

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Vydáno v:BMC Immunol
Hlavní autoři: Berga-Bolaños, Rosa, Sharma, Archna, Steinke, Farrah C., Pyaram, Kalyani, Kim, Yeung-Hyen, Sultana, Dil A., Fang, Jessie X., Chang, Cheong-Hee, Xue, Hai-Hui, Heller, Nicola M., Sen, Jyoti Misra
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615569/
https://ncbi.nlm.nih.gov/pubmed/26482437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0121-0
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