Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation

The activation of translation contributes to malignant transformation and is an emerging target for cancer therapies. RNA G-quadruplex structures are general inhibitors of cap-dependent mRNA translation and were recently shown to be targeted for oncoprotein translational activation. In contrast howe...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Cammas, Anne, Dubrac, Alexandre, Morel, Benjamin, Lamaa, Assala, Touriol, Christian, Teulade-Fichou, Marie-Paule, Prats, Hervé, Millevoi, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615567/
https://ncbi.nlm.nih.gov/pubmed/25826664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017236
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