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RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity

Aptamers are an emerging class of highly specific targeting ligands. They can be selected in vitro for a large variety of targets, ranging from small molecules to whole cells. Most aptamers selected are nucleic acid-based, allowing chemical synthesis and easy modification. Although their properties...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Mittelberger, Florian, Meyer, Cindy, Waetzig, Georg H, Zacharias, Martin, Valentini, Erica, Svergun, Dmitri I, Berg, Katharina, Lorenzen, Inken, Grötzinger, Joachim, Rose-John, Stefan, Hahn, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615291/
https://ncbi.nlm.nih.gov/pubmed/26383776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1079681
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