d(GGGT)(4) and r(GGGU)(4) are both HIV-1 inhibitors and interleukin-6 receptor aptamers

Aptamers are oligonucleotides that bind targets with high specificity and affinity. They have become important tools for biosensing, target detection, drug delivery and therapy. We selected the quadruplex-forming 16-mer DNA aptamer AID-1 [d(GGGT)(4)] with affinity for the interleukin-6 receptor (IL-...

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Détails bibliographiques
Auteurs principaux: Magbanua, Eileen, Zivkovic, Tijana, Hansen, Björn, Beschorner, Niklas, Meyer, Cindy, Lorenzen, Inken, Grötzinger, Joachim, Hauber, Joachim, Torda, Andrew E., Mayer, Günter, Rose-John, Stefan, Hahn, Ulrich
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594281/
https://ncbi.nlm.nih.gov/pubmed/23235494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.22951
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