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RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation
Site-specific hypermethylation of tumor suppressor genes accompanied by genome-wide hypomethylation are epigenetic hallmarks of malignancy. However, the molecular mechanisms that drive these linked changes in DNA methylation remain obscure. DNA methyltransferase 1 (DNMT1), the principle enzyme respo...
Gorde:
| Argitaratua izan da: | Cell Cycle |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615144/ https://ncbi.nlm.nih.gov/pubmed/25485502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.950886 |
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