Cargando...
RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation
Site-specific hypermethylation of tumor suppressor genes accompanied by genome-wide hypomethylation are epigenetic hallmarks of malignancy. However, the molecular mechanisms that drive these linked changes in DNA methylation remain obscure. DNA methyltransferase 1 (DNMT1), the principle enzyme respo...
Guardado en:
| Publicado en: | Cell Cycle |
|---|---|
| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2014
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615144/ https://ncbi.nlm.nih.gov/pubmed/25485502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.950886 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|