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Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic inducers, and thus the ability to resume cell divisi...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Main Authors: Müllers, Erik, Cascales, Helena Silva, Jaiswal, Himjyot, Saurin, Adrian T, Lindqvist, Arne
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615111/
https://ncbi.nlm.nih.gov/pubmed/25486360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2015.945831
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