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Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic inducers, and thus the ability to resume cell divisi...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Müllers, Erik, Cascales, Helena Silva, Jaiswal, Himjyot, Saurin, Adrian T, Lindqvist, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615111/
https://ncbi.nlm.nih.gov/pubmed/25486360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2015.945831
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