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Bimodal regulation of p21(waf1) protein as function of DNA damage levels

Human p21(Waf1) protein is well known for being transcriptionally induced by p53 and activating the cell cycle checkpoint arrest in response to DNA breaks. Here we report that p21(Waf1) protein undergoes a bimodal regulation, being upregulated in response to low doses of DNA damage but rapidly and t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Cycle
मुख्य लेखकों: Buscemi, G, Ricci, C, Zannini, L, Fontanella, E, Plevani, P, Delia, D
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615108/
https://ncbi.nlm.nih.gov/pubmed/25486478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.946852
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